Retinopathy of Prematurity (ROP) – Diagnosis & Treatment

Retinopathy of Prematurity (ROP) is a potentially serious eye condition that affects premature babies. It occurs due to abnormal development of the retinal blood vessels, which can interfere with normal vision development and, in severe cases, lead to permanent vision loss. At Agashe Hospital, Mumbai, our pediatric ophthalmology team provides timely ROP screening, accurate diagnosis, and advanced treatment to protect vision in premature infants.

What Is Retinopathy of Prematurity (ROP)?

The retina is the light-sensitive layer at the back of the eye that is essential for vision. In babies born prematurely, retinal blood vessels may not develop normally. ROP occurs when these vessels grow abnormally, potentially causing scarring or pulling of the retina. While many mild cases resolve on their own, severe ROP requires urgent medical attention to prevent long-term visual impairment.

Which Babies Are at Risk?

ROP primarily affects babies who are:

  • Born prematurely (usually before 32 weeks of gestation)
  • Having low birth weight
  • Requiring oxygen therapy or prolonged NICU care

The risk increases with earlier gestational age and lower birth weight. Because ROP may not show visible symptoms initially, routine ROP screening is critical for all at-risk infants.

Signs and Symptoms of ROP

In the early stages, ROP does not cause obvious external signs. As the condition advances, parents may notice:

  • Abnormal eye movements
  • White or cloudy appearance of the pupil
  • Poor visual response

However, these signs often appear late. This is why scheduled ROP eye examinations by a trained ROP specialist are essential even when the baby appears normal.

Screening and Diagnosis of ROP

ROP diagnosis is made through a specialized retinal examination performed by a pediatric ophthalmologist. At Agashe Hospital, ROP screening is carried out in accordance with established guidelines and includes:

  • Dilated retinal examination
  • Assessment of retinal blood vessel growth
  • Classification of disease severity and risk of progression

Early diagnosis allows timely intervention and significantly improves visual outcomes.

Treatment Options for Retinopathy of Prematurity

Treatment depends on the stage and severity of ROP. Many mild cases only require careful monitoring. When treatment is needed, options include:

  • Laser treatment: Used to stop abnormal blood vessel growth and reduce the risk of retinal detachment
  • Anti-VEGF injections: Medications injected into the eye to control abnormal vessel development in selected cases
  • Surgery: Reserved for advanced stages where retinal detachment has occurred

ROP treatment aims to preserve vision and prevent further damage. Babies who receive treatment require long-term follow-up to monitor visual development.

Long-Term Follow-Up and Vision Care

Even after successful ROP treatment, children born prematurely may have a higher risk of:

  • Refractive errors (glasses requirement)
  • Squint (strabismus)
  • Amblyopia (lazy eye)

Regular eye check-ups throughout childhood are essential to support healthy visual development.

Why Choose Agashe Hospital for ROP Care?

Expert Pediatric Ophthalmology Care: Extensive experience in ROP screening and treatment

Timely NICU-Linked Screening: Coordinated care for premature infants

Advanced Treatment Options: Laser and injection-based therapies when indicated

Continuity of Care: Long-term monitoring for vision development and childhood eye conditions

FAQs

ROP cannot always be prevented, but early screening and timely treatment can prevent vision loss.

No. Many premature babies do not develop ROP, and many mild cases resolve without treatment.

Procedures are performed with appropriate anaesthesia and monitoring to ensure safety and comfort.

Many children achieve good vision, especially with early detection and follow-up care, though some may need glasses or further treatment.

Follow-up often continues through childhood to monitor vision development and detect related eye conditions early.